Coronavirus A.30 variant ‘efficiently evades’ antibodies induced by Pfizer & AstraZeneca vaccines – lab study

The A.30 variant of the coronavirus, detected in Angola and Sweden, is highly resistant to antibodies induced by the Pfizer and AstraZeneca vaccines, a new lab study has shown.

A team from Germany looked at the rare A.30 variant that was first recorded in Tanzania and later detected in several patients in Angola and Sweden this spring. They compared the mutation to the Beta and Eta variants. Beta was chosen because it has “the highest level” of resistance to antibodies, the researchers said.

According to the study published in the peer-reviewed journal Cellular & Molecular Immunology this week, the A.30 variant showed improved ability to enter most host cells, including kidney, liver, and lung cells.

The mutation “enters certain cell lines with increased efficiency and evades antibody-mediated neutralization,” the study found.

Leave a Reply

Your email address will not be published. Required fields are marked *